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While chemically insignificant to lysine itself, it’s price noting that lysine is connected to dextroamphetamine to form the prodrug lisdexamfetamine (Vyvanse). The accompanying urinary cysteine results because the same deficient amino acid transporter is normally current within the kidney as well. In the gastrointestinal tract , the lysine molecule is cleaved from the dextroamphetamine.
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Widespread posttranslational modifications include methylation of the ε-amino group, giving methyl- , dimethyl- , and trimethyllysine The latter occurs in calmodulin Different posttranslational modifications at lysine residues embody acetylation , sumoylation , and ubiquitination Collagen contains hydroxylysine , which is derived from lysine by lysyl hydroxylase – Glycosylation of hydroxylysine residues within the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell In opsins like rhodopsin and the visual opsins (encoded by the genes OPN1SW , OPN1MW , and OPN1LW ), retinaldehyde forms a Schiff base with a conserved lysine residue, and interaction of sunshine with the retinylidene group causes signal transduction in color vision (See visible cycle for details).
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